The second program focuses on the impact of hospital-acquired infections and medical errors.

The second program focuses on the impact of hospital-acquired infections and medical errors in two institutions, and follows the efforts of physicians who are challenging their colleagues to live up to their oath to "First Do No Harm." In Pittsburgh, Pennsylvania, Chief of Medicine Dr. Richard Shannon is confronting an epidemic of hospital-acquired infections that are shattering the lives of their victims. Hackensack University Medical Center in New Jersey is engaged in an effort to completely transform the way the institution delivers care. The goal in both hospitals is to ensure that the people trusted to provide safe and effective medical treatment do not harm patients.